the intestinal phase of stomach digestion is triggered by partially digested nutrients filling the pylorus.
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Phases of Digestion
Phases of Digestion
Phases of Digestion Cephalic Phase
The cephalic phase of gastric secretion occurs before food enters the stomach due to neurological signals.
LEARNING OBJECTIVES
Outline the cephalic phase of digestion
KEY TAKEAWAYS
Key Points
The cephalic phase of gastric secretion is initiated by the sight, smell, thought or taste of food.
Neurological signals originate from the cerebral cortex and in the appetite centers of the amygdala and hypothalamus.
This enhanced secretory activity is a conditioned reflex.
This phase of secretion normally accounts for about 20 percent of the gastric secretion associated with eating a meal.
Key Terms
conditioned reflex: A response, to a stimulus, that has been acquired by operant conditioning.cephalic phase: This occurs before food enters the stomach, especially while it is being eaten.The cephalic phase of gastric secretion occurs before food enters the stomach, especially while it is being eaten. It results from the sight, smell, thought, or taste of food; and the greater the appetite, the more intense is the stimulation.
Neurogenic signals that initiate the cephalic phase of gastric secretion originate from the cerebral cortex, and in the appetite centers of the amygdala and hypothalamus. They are transmitted through the dorsal motor nuclei of the vagi, and then through the vagus nerve to the stomach.
This phase of secretion normally accounts for about 20% of the gastric secretions that are associated with eating a meal. Since this enhanced secretory activity is brought on by the thought or sight of food it is a conditioned reflex—it only occurs when we like or want food. When one’s appetite is depressed this part of the cephalic reflex is inhibited.
The cephalic phase causes ECL cells to secrete histamine and increase HCl acid in the stomach. There will also be an influence on G cells to increase gastrin circulation.
Chain of Events for the Nervous System and Hormone System
Thinking of food (i.e., smell, sight) stimulates the cerebral cortex.
The cerebral cortex sends messages to the hypothalamus, the medulla, and the parasympathetic nervous system via the vagus nerve, and to the stomach via the gastric glands in the walls of the fundus and the body of stomach.
The gastric glands secrete gastric juice.
When food enters the stomach, the stomach stretches and activates stretch receptors.
The stretch receptors send a message to the medulla and then back to the stomach via the vagus nerve.
The gastric glands secrete more gastric juice.
Chemical stimuli (i.e., partially digested proteins, caffeine) directly activate G cells (enteroendocrine cells) that are located in the pyloric region of the stomach to secrete gastrin; this in turn stimulates the gastric glands to secrete gastric juice.
Gastric Phase
The gastric phase is a period in which swallowed food activates gastric activity in the stomach.
LEARNING OBJECTIVES
Outline the gastric phase of digestion
KEY TAKEAWAYS
Key Points
The gastric phase accounts for about two-thirds of gastric secretions.
Ingested food stimulates gastric activity by stretching the stomach and raising the pH of its contents; this causes a cascade of events that leads to the release of hydrochloric acid by the parietal cells that lower the pH and break apart the food.
Gastric secretion is stimulated chiefly by three chemicals: acetylcholine (ACh), histamine, and gastrin.
Below pH of 2, stomach acid inhibits the parietal cells and G cells; this is a negative feedback loop that winds down the gastric phase as the need for pepsin and HCl declines.
Key Terms
gastric phase: The second phase of digestion that follows mastication (chewing) and takes place in the stomach.The gastric phase is a period in which swallowed food and semi-digested protein ( peptides and amino acids ) activate gastric activity. About two-thirds of gastric secretion occurs during this phase.
Ingested food stimulates gastric activity in two ways: by stretching the stomach and by raising the pH of its contents.
Stretching activates two reflexes: a short reflex is mediated through the myenteric nerve plexus; and a long reflex is mediated through the vagus nerves and brainstem.
Gastric Secretion
Gastric secretion is stimulated chiefly by three chemicals:
Acetylcholine (ACh). This is secreted by the parasympathetic nerve fibers of both the short and long reflex pathways.
Histamine. This is a paracrine secretion from the enteroendocrine cells in the gastric glands.
Gastrin. This is a hormone produced by enteroendocrine G cells in the pyloric glands.
All three of these stimulate parietal cells to secrete hydrochloric acid and intrinsic factor. The chief cells secrete pepsinogen in response to gastrin and especially ACh, and ACh also stimulates mucus secretion.
As dietary protein is digested, it breaks down into smaller peptides and amino acids that directly stimulate the G cells to secrete even more gastrin: this is a positive feedback loop that accelerates protein digestion.
Small peptides also buffer the stomach acid so the pH does not fall excessively low. As digestion continues and these peptides empty from the stomach, the pH drops lower and lower. Below pH of 2, stomach acid inhibits the parietal cells and G cells: this is a negative feedback loop that winds down the gastric phase as the need for pepsin and HCl declines.
Source : courses.lumenlearning.com
Associate Degree Nursing Physiology Review
Digestive System Content
Digestive System Anatomy
Basic Organization of the Digestive Tract
Functions of the GI Tract
Peristalsis/Segmentation
Regulation of Digestion
Intrinsic/Neuronal/Extrinsic Controls
Digestion
Oral Cavity Functions
Saliva
Deglutition (Swallowing)
Functions of the Stomach
Regulation of Gastric Secretion
Regulation of HCl Secretion
Gastric Contractile Activity
Regulation of Gastric Emptying
Digestion in Stomach
Small Intestine
Hormones That Regulate Digestion
Duodenum Liver Gallbladder
Regulation of Bile Release
Pancreas
Digestion in the Small Intestine
Absorption of Nutrients Occurs in the Small Intestine
Control of Intestinal Motility
Large Intestine Rectum
Chemical Digestion and Absorption of Carbohydrates/proteins/lipids/fatty acid/nucleic acids
Absorption of Water
Absorption of Electrolytes
Digestive System
The digestive system is the system of the body that mechanically and chemically breaks down food.
It takes about 12 to 24 hours to completely break down food.
The digestive organs are usually divided into two main groups:
the gastrointestinal tract
the accessory organs
Click here for an animation that provides an overview of the digestive system organs and function.
Practice questions follow the animation.
Gastrointestinal (GI) tract (also called alimentary canal or digestive tract)The GI tract is a continuous tube running from the mouth to the anus. It measures about 9 m (30 ft) in length. The GI tract digests and absorbs food.
It includes the following organs:
mouth pharynx esophagus stomach small intestine large intestine
Accessory Digestive OrgansIncludes the following organs:
teeth tongue gallbladder salivary glands liver, and pancreas
Basic Organization of the Digestive Tract
The digestive tract from the esophagus to the large intestine is made up of the same 4 basic tissue layers:
1. Mucosa (Mucous Membrane)Innermost layer
Lines the lumen of the digestive tract
Is a mucous membrane made of epithelium, connective tissue, and a very thin layer of smooth muscle
Has many blood and lymphatic vessels to absorb nutrients
Has lots of lymphatic nodules to fight pathogens.
2. SubmucosaMade of connective tissue
Has lots of blood and lymphatic vessels that receive absorbed food molecules
Has lymphatic tissue.
Has a nerve plexus that regulate movements and secretions of the digestive tract
In the esophagus and duodenum the submucosa also has mucin-secreting glands
3. Muscularis ExternaMade of skeletal muscle or smooth muscle.
The mouth, pharynx, and superior and middle parts of the esophagus, and anus contain skeletal muscle.
The lower part of the esophagus and the rest of the GI tract contain 2 or 3 layers of smooth muscle.
Has a nerve plexus here that controls the frequency and strength of contraction of smooth muscle.
4. Adventitia or SerosaAdventitia = areolar connective tissue with dispersed collagen and elastic fibers (retroperitoneal organs, e.g. ascending colon)Serosa = same as adventitia but covered by a visceral peritoneum (intraperitoneal, e.g. stomach)Functions of the GI TractThe GI tract is a “disassembly” line, nutrients become more available to the body in each step:
Ingestiontaking in of food through the mouth
Mechanical DigestionPhysical breakdown of solid foods
Masses of food are broken into smaller parts
tongue and teeth physically break down the food
stomach mixes the food.
small intestine also physically breaks down food when the secretion of bile emulsifies or breaks up fat globules into smaller droplets
Propulsion (motility)swallowing and peristalsis
Secretionrelease of hormones and enzymes
Chemical DigestionChemical breakdown of food by enzymes into smaller components that can be absorbed by the epithelium of the digestive tract
For example starch is broken down into the disaccharide maltose in the oral cavity. Later the disaccharides are broken down into monosaccharides in the small intestine.
Click here for an animation that reviews how enzymes (such as sucrase) can break down foods (such as a disaccharide).
SecretionRelease of water, acids, enzymes, and buffers by the digestive tract and by the accessory organs into the lumen of the digestive tract
AbsorptionMovement of small organic molecules, electrolytes, vitamins, and water across the digestive epithelium and into the blood and lymph
Excretion (Defecation)Removal of waste products which are first compacted and then discharged during defecation
Chapter 23 Anatomy Flashcards
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Chapter 23 Anatomy
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Which major process involves the removal of water from intestinal contents?
mechanical breakdown
defecation absorption ingestion
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absorption
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Where does the process of segmentation occur?
anus esophagus stomach small intestine
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small intestine
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1/40 Created by ryan_moran77
Terms in this set (40)
Which major process involves the removal of water from intestinal contents?
mechanical breakdown
defecation absorption ingestion absorption
Where does the process of segmentation occur?
anus esophagus stomach small intestine small intestine
How would you classify chewing food?
digestion ingestion propulsion
mechanical breakdown
mechanical breakdown
Which of the following functions is NOT correctly matched with its description?
-mechanical breakdown: churning movements in the GI tract
-absorption; passage of digested nutrients into the blood or lymph
-propulsion: physical breakdown of ingested food in the GI tract
-ingestion: intake of food nutrients
-propulsion: physical breakdown of ingested food in the GI tract
Which of the following is NOT a means of mechanically breaking down food?
mastication segmentation peristalsis churning peristalsis
Which organ of the digestive tract is the body's major digestive organ?
liver stomach large intestine small intestine small intestine
Which layer of the alimentary canal is constructed from either stratified squamous or simple columnar epithelium?
mucosa serosa submucosa muscularis externa mucosa
Which layer of the alimentary canal is responsible for segmentation and peristalsis?
muscularis externa serosa submucosa mucosa muscularis externa
The __________ is the serous membrane that lines the abdominal organs.
visceral peritoneum omenta mesentery parietal peritoneum visceral peritoneum
Which layer of the digestive tract controls digestive propulsion?
mucosa submucosa serosa muscularis externa muscularis externa
The uvula is an extension of the __________.
oral vestibule lingual frenulum soft palate
palatopharyngeal arch
soft palate
Which of the following is NOT a function of saliva?
-Saliva moistens food and helps compact it into a bolus.
-Saliva cleanses the mouth.
-Saliva contains enzymes that begin the chemical breakdown of proteins.
-Saliva dissolves food chemicals so that they can be tasted.
-Saliva contains enzymes that begin the chemical breakdown of proteins.
Which of the following inhibits salivation?
the sight or smell of food
being stressed or frightened
relaxing after a meal
ingestion of spicy foods
being stressed or frightened
How many total permanent teeth should an adult have, assuming none have been lost or removed?
8 16 20 32 32
The deciduous dentition consists of __________ teeth.
10 16 20 32 20
Which digestive process does NOT occur in the mouth?
segmentation
mechanical breakdown
digestion ingestion segmentation
Which layer of the stomach contains the gastric pits that secrete mucous, acid, and digestive enzymes?
serosa mucosa submucosa muscularis externa mucosa
Which of these structures is found in the stomach but nowhere else in the alimentary canal?
a circular muscle layer
an oblique muscle layer
a lining of columnar epithelium
mucus-forming cells
an oblique muscle layer
Which area of the stomach adjoins the small intestine?
body cardia pylorus fundus pylorus
Which of the following constitute a portal triad?
-three lobules sharing a common central vein
-the hepatic artery and two hepatic veins
-a bile duct along with a portal venule and arteriole
-the porta hepatis
a bile duct along with a portal venule and arteriole
Which of the following best describes the capillary wall structure found in the liver lobules?
-The walls are continuous, only allowing small molecules and water to pass through.
-The walls have windows that allow small proteins to pass through but not cells.
-The capillary walls have openings that allow large proteins and small cells to pass through.
-The walls only allow water to pass through.
-The capillary walls have openings that allow large proteins and small cells to pass through.
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