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    Question

    Progression of cell cycle is regulated by the concentration of which type of molecule?

    A

    Centrosomes

    B

    Cyclin-dependent kinases

    C

    Cyclins

    D

    Microtubule

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    Progression of cell cycle is regulated by the concentration of which type of molecule

    Watch complete video answer for “Progression of cell cycle is regulated by the conce” of Biology Class 12th. Get FREE solutions to all questions from chapter CELL CYCLE (CELL DIVISION).

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    Cell Cycle (Cell Division)

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    Question : Progression of cell cycle is regulated by the concentration of which type of molecule

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    Step by step video solution for "Progression of cell cycle is regulated by the concentration of which type of molecule" by Biology experts to help you in doubts & scoring excellent marks in Class 12 exams.

    Updated On: 12-03-2022

    Video Solution: Progression of cell cycle is regulated by the concentration of which type of molecule

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    Text Solution A Centrosomes B

    Cyclin dependent kinases

    C Cyclins D Microtubules. Answer C Transcript

    hello everyone we have a question here progression of cell cycle is regulated by concentration of which type of molecule option one centrosomes option to cyclin-dependent kinases option 3 cyclin option for Microtek ok first of all the first option is central zone no centrosomes actually helps in Sun cycle by creating spindle fibres spindle fibre ok but they do not the regulate the progression of cell cycle ok they are helpful only when surgical is already started ok they do not regulate the progression of it ok to Central zone is not a correct answer second option is cyclin-dependent kinases cyclin-dependent kinases why they are known as cyclin-dependent kinases because they are activated by cycling

    activated by cycling ok in the short form they are also known as CD case right now what is the function of cyclin dependent kinase is actually they help the phosphorylation of molecules in addition of phosphate group phosphorylation now this phosphorylation create a signal ok that will tell the cell to enter the next stage of cell cycle ok means to enter cell cycle and cell cycle Sudhar jao CD case are actually essential for the regulation of progression of cell cycle did tell the cell to enter the next eight ok so that regulate the progression of cell cycle this is the correct answer in cycling now the function of cycling is to activate CD case

    wait CD case ok it does not directly regulate the provision of cell cycle but it helps in activation of CD case so it is not the correct answer because it is not directly involved in regulation ok third option is microwave use of microtubules are also protein ok that help in cell cycle but not regulate the cell cycle the correct answer the above question will be correct answer will be option to I hope you understood thank you

    Question Details till 22/03/2022

    Question

    Progression of cell cycle is regulated by the concentration of which type of molecule

    Chapter Name Cell Cycle (Cell Division)Subject Biology (more Questions)Class 12thType of Answer VideoQuestion Language

    In Video - English In Text - English

    Students Watched 3.0 K+Students Liked 400+Question Video Duration 2m33s

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    Chapter 12 (control of the cell cycle) Flashcards

    Start studying Chapter 12 (control of the cell cycle). Learn vocabulary, terms, and more with flashcards, games, and other study tools.

    Chapter 12 (control of the cell cycle)

    After S phase, what comprises a single chromosome?

    Click card to see definition 👆

    two sister chromatids

    Click again to see term 👆

    Progression through the cell cycle is regulated by oscillations in the concentration of which type of molecule?

    Click card to see definition 👆

    Cyclins

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    1/21 Created by gsolini

    Terms in this set (21)

    After S phase, what comprises a single chromosome?

    two sister chromatids

    Progression through the cell cycle is regulated by oscillations in the concentration of which type of molecule?

    Cyclins

    What major events occur during anaphase of mitosis?

    during anaphase, the sister chromatids are separated and migrate toward opposite poles of the cell (via microtubule depolymerization)

    What events in the cell cycle must be completed successfully for daughter cells to share an identical complement of chromosomes?

    -chromosomes must be correctly duplicated

    -kinetochores must properly attach to microtubules during prometaphase

    -chromosomes must be properly aligned and separated during mitosis

    -cytokinesis must properly divide the cytoplasm into two daughter cells

    What evidence suggests that during anaphase, kinetochore microtubules shorten at the kinetochore (and not the spindle apparatus)?

    daughter chromosomes moved faster toward the poles than the marked regions of fluorescently labeled kinetochore microtubules

    Which could lead to uncontrolled cell growth in cancer? (more than 1)

    (a) overexpression of MFP activity

    (b)nonfunctional Rb protein

    (c)overexpression of G1 cyclin

    (d)nonfunctional E2F protein

    (a) False (b) True (c)True

    (d) false (because E2F protein is what triggers the production of S-phase proteins)

    Outline how growth factors work to induce S-phase

    (a) growth factors stimulate the production of cyclins and E2F

    (b) cyclin binds to cdk and is phosphorylated at both sites to deactivate

    (c)Rb inactivates E2F by binding to it

    (d)inactivating phosphate is removed and active Cdk phosphorylated Rb

    (e)phosphorylated Rb releases E2F

    (f)E2F triggers production of S-phase proteins

    compare and contrast the effects of removing growth factors from normal human cells and cancerous human cells

    In normal human cells, removal of growth factors would result in the arrest of the cell cycle, since there would not be enough cell growth and there would be no signal to trigger S-phase. In cancer cells, the G1 checkpoint is bypassed, allowing the cells to continue through the cell cycle despite less growth and possible damage.

    What are the phases of mitosis and brief descriptions?

    Prophase - chromosomes condense and the spindle apparatus begins to form

    prometaphase - nuclear envelope breaks down and microtubules contact chromosomes at the kinetochores

    metaphase - chromosomes migrate to the middle of the cell and align in the center

    anaphase - sister chromatids separate into daughter chromosomes and are pulled to opposite poles by the spindle apparatus

    telophase - the nuclear envelope re-forms and chromosomes decondense

    what are the phases of the cell cycle? What occurs during the gap phases? What is the G0 phase?

    (1) G1, S, G2, M

    (2) Gap phases are where cell growth, organelle replication, mitotic protein preparation (MPK), and cytoplasmic growth occur

    (3) the G0 phase is a phase of cell cycle arrest where the cell exits the cell cycle and stops growing and dividing

    What is MPF

    M-phase promoting factor - this is a cyclin-cdk dimer that when activated at the correct phosphorylation center will phosphorylate proteins that are needed to initiate mitosis

    What is Cdk

    cyclin-dependent kinase - this is an enzyme that is functional only when bound to cyclin and is further activated by other modifications

    what is cyclin

    regulatory protein whose concentrations fluctuate cyclically throughout the cell cycle. Binds to cdk and controls the cell cycle.

    How are Cdks activated? Explain the accumulation and degradation of cyclin in cells.

    (a) Cdks are activated by binding to cyclin to form a cyclin-cdk dimer

    (b)cyclin concentration grows steadily thorughout the cell cycle. Growth beings in G1 and peaks in M-phase (during metaphase), and is then destroyed before G1 occurs again in daughter cells.

    What is the function of Cdk?

    Cdk binds to cyclin to form MPK. The Cdk portion of MPK (is a kinase), when phosphorylated in the proper place, triggers the phosphorylation of other proteins that eventually start the M-phase

    What are the three cell-cycle checkpoints?

    G1 - cell is correct size, has enough nutrients, proper social signals (growth factors), DNA is undamaged

    G2 - DNA is undamaged, chromosomes have successfully replicated, and active MPK is accumulating (MPK present)

    M - chromosomes have attached to the spindle apparatus and are properly segregated (MPF absent)

    Explain how the G1 checkpoint is under social control

    social signals in the form of growth factors are necessary for the cell to progress from G1 checkpoint to the S-phase (through E2F activation of S-phase proteins)

    What characterizes cancer on a cellular level?

    cancer is characterized by defects in one or more of the cell cycle checkpoints, resulting in out-of-control cellular growth and division (and the accumulation of genetic mutations)

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